STM32L4R5 and STM32L4S5 devices extend the ultra‐low‐power portfolio and performance with an ARM® Cortex®‐M4 core with DSP and floating‐point unit (FPU) at 120 MHz.
- The STM32L4R5 portfolio offers from 1 to 2 Mbytes of Flash memory and from 100 to 169-pin packages.
- The STM32L4S5 ias available with 2 Mbytes of Flash memory and provides an additional encryption accelerator engine (AES, HASH).

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The STM32Cube.AI is an extension pack of the widely used STM32CubeMX configuration and code generation tool enabling AI on STM32 Arm® Cortex®-M-based microcontrollers.
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- STM32L4R5QI Ultra-low-power with FPU ARM Cortex-M4 MCU 120 MHz with 2048 kbytes Flash, USB OTG, DFSDM, CHROM-ART
- STM32L4R5VI Ultra-low-power with FPU ARM Cortex-M4 MCU 120 MHz with 2048 kbytes Flash, USB OTG, DFSDM, CHROM-ART
- STM32L4R5VG Ultra-low-power with FPU ARM Cortex-M4 MCU 120 MHz with 1024 kbytes Flash, USB OTG, DFSDM, CHROM-ART
- STM32L4S5AI Ultra-low-power with FPU ARM Cortex-M4 MCU 120 MHz with 2048 kbytes Flash, USB OTG, DFSDM, CHROM-ART, AES-256, HASH
- STM32L4R5QG Ultra-low-power with FPU ARM Cortex-M4 MCU 120 MHz with 1024 kbytes Flash, USB OTG, DFSDM, CHROM-ART
- STM32L4S5VI Ultra-low-power with FPU ARM Cortex-M4 MCU 120 MHz with 2048 kbytes Flash, USB OTG, DFSDM, CHROM-ART, AES-256, HASH
- STM32L4R5ZG Ultra-low-power with FPU ARM Cortex-M4 MCU 120 MHz with 1024 kbytes Flash, USB OTG, DFSDM, CHROM-ART
- STM32L4S5QI Ultra-low-power with FPU ARM Cortex-M4 MCU 120 MHz with 2048 kbytes Flash, USB OTG, DFSDM, CHROM-ART, AES-256, HASH
- STM32L4R5AI Ultra-low-power with FPU ARM Cortex-M4 MCU 120 MHz with 2048 kbytes Flash, USB OTG, DFSDM, CHROM-ART
- STM32L4R5ZI Ultra-low-power with FPU ARM Cortex-M4 MCU 120 MHz with 2048 kbytes Flash, USB OTG, DFSDM, CHROM-ART
- STM32L4S5ZI Ultra-low-power with FPU ARM Cortex-M4 MCU 120 MHz with 2048 kbytes Flash, USB OTG, DFSDM, CHROM-ART, AES-256, HASH
- STM32L4R5AG Ultra-low-power with FPU ARM Cortex-M4 MCU 120 MHz with 1024 kbytes Flash, USB OTG, DFSDM, CHROM-ART