STM32F105/107器件采用Cortex-M3内核，CPU最高速度达72 MHz。它们面向需要连接功能和实时性能的应用，例如工业控制、安全应用控制面板、UPS和家用音响。
该系列具有64~256KB片上Flash存储器、64KB SRAM和14个通信接口。
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STM32F105VC
Mainstream Connectivity line, Arm Cortex-M3 MCU with 256 Kbytes of Flash memory, 72 MHz CPU, CAN, USB 2.0 OTG
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STM32F105VB
Mainstream Connectivity line, Arm Cortex-M3 MCU with 128 Kbytes of Flash memory,72 MHz CPU, CAN, USB 2.0 OTG
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STM32F107RB
Mainstream Connectivity line, Arm Cortex-M3 MCU with 128 Kbytes of Flash memory, 72 MHz CPU, Ethernet MAC, CAN and USB 2.0 OTG
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STM32F107RC
Mainstream Connectivity line, Arm Cortex-M3 MCU with 256 Kbytes of Flash memory, 72 MHz CPU, Ethernet MAC, CAN and USB 2.0 OTG
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STM32F107VB
Mainstream Connectivity line, Arm Cortex-M3 MCU with 128 Kbytes of Flash memory, 72 MHz CPU, Ethernet MAC, CAN and USB 2.0 OTG
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STM32F105R8
Mainstream Connectivity line, Arm Cortex-M3 with 64 Kbytes of Flash memory, 72 MHz CPU, CAN, USB 2.0 OTG
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STM32F105RB
Mainstream Connectivity line, Arm Cortex-M3 MCU with 128 Kbytes of Flash memory, 72 MHz CPU, CAN, USB 2.0 OTG
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STM32F105RC
Mainstream Connectivity line, Arm Cortex-M3 MCU with 256 Kbytes of Flash memory, 72 MHz CPU, CAN, USB 2.0 OTG
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STM32F105V8
Mainstream Connectivity line, Arm Cortex-M3 MCU with 64 Kbytes of Flash memory, 72 MHz CPU, CAN, USB 2.0 OTG
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STM32F107VC
Mainstream Connectivity line, Arm Cortex-M3 MCU with 256 Kbytes of Flash memory, 72 MHz CPU, Ethernet MAC, CAN and USB 2.0 OTG
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